Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ JmjC Histone Demethylase Inhibitor, n-Octyl-IOX1
A cell-permeable, superior inhibitor of Jumonji C domain histone lysine demethylase. About 30 fold more potent than IOX1 (EC50 = 3.8 μM for KDM4A in HeLa cells vs. 100 μM for IOX1).
MilliporeSigma™ Calbiochem™ Diphenyleneiodonium Chloride
A cell-permeable, irreversible inhibitor of endothelial nitric oxide synthase (eNOS).
MilliporeSigma™ Calbiochem™ NF-κB Activation Inhibitor VII, CID-2858522
The NF-κB Activation Inhibitor VII, CID-2858522 controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ NS-398
A cell-permeable selective inhibitor of COX-2 in vitro.
MilliporeSigma™ Calbiochem™ L-(–)-Norepinephrine-(+)-bitartrate
α,β-Adrenergic agonist.
MilliporeSigma™ Calbiochem™ VEGFR Tyrosine Kinase Inhibitor II
The VEGFR Tyrosine Kinase Inhibitor II, also referenced under CAS 269390-69-4, controls the biological activity of VEGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Spautin-1
A quinazolin compound that acts as a specific and potent inhibitor of autophagy and promotes Vps34 PI 3-kinase complex degradation by blocking the activity of USP 10 (IC50 = 580nM) and USP 13 (IC50 = 690nM) deubiquitinating enzymes
MilliporeSigma™ Calbiochem™ Ezrin Inhibitor, NSC668394
The Ezrin Inhibitor, NSC668394 controls the biological activity of Ezrin.
MilliporeSigma™ Calbiochem™ S1P4 Receptor Antagonist, CYM50358
The S1P4 Receptor Antagonist, CYM50358 controls the biological activity of S1P4 Receptor. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ ProRS Inhibitor, Halofuginone
A cell-permeable racemic mixture of Halofuginone that inhibits of prolyl-tRNA synthetase.
MilliporeSigma™ Calbiochem™ Gambogic Acid, Garcinia hanburyi
A cell-permeable caspase activator and an apoptosis inducer that was originally isolated from gamboge resin for its antimicrobial properties.
MilliporeSigma™ Calbiochem™ ERO1 Inhibitor II, EN460
A cell-permeable thiol reactive enone (EN) compound that selectively interacts with the active-site cysteine of reduced, active form of ERO1α and inhibits its activity (IC50
MilliporeSigma™ Calbiochem™ Caspase Inhibitor I, Biotin Conjugate
The Caspase Inhibitor I, Biotin Conjugate controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Serine Protease Inhibitor Cocktail Set I
The Serine Protease Inhibitor Cocktail Set I controls the biological activity of Serine Protease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ JAK2 Inhibitor III, SD-1029
The JAK2 Inhibitor III, SD-1029, also referenced under CAS 118372-34-2, controls the biological activity of JAK2.