Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ TAPI-0
TAPI-0, CAS 143457-40-3, is a hydroxamate-based inhibitor of collagenase, gelatinase, and TACE (TNF-α converting enzyme/ADAM17; IC50 = 100 nM).
MilliporeSigma™ Calbiochem™ ALDH2 Agonist, Alda-1
The ALDH2 Agonist, Alda-1, also referenced under CAS 349438-38-6, controls the biological activity of ALDH2. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
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MilliporeSigma™ Calbiochem™ MALT1 Inhibitor II, Mepazine Hydrochloride
MALT1 Inhibitor II, Mepazine HCl, CAS 60-89-9, is a cell-permeable inhibitor of MALT1. Does not affect caspase-3 or -8 activities.
MilliporeSigma™ Calbiochem™ Metastin (45-54)
A decapeptide with C-terminally amidated LRF-motif that acts as a potent and selective agonist of AXOR12 and hOT7T175 (a novel human G-protein-coupled receptors).
MilliporeSigma™ Calbiochem™ PIM1/2 Kinase Inhibitor VI
The PIM1/2 Kinase Inhibitor VI, also referenced under CAS 587852-28-6, controls the biological activity of PIM1/2.
MilliporeSigma™ Calbiochem™ CBP-CREB Interaction Inhibitor
The CBP-CREB Interaction Inhibitor, also referenced under CAS 92-78-4, controls the biological activity of CBP-CREB.
MilliporeSigma™ Calbiochem™ c-Myc Inhibitor
The c-Myc Inhibitor, also referenced under CAS 403811-55-2, controls the biological activity of c-Myc.
MilliporeSigma™ Calbiochem™ InSolution™ Foxo1 Inhibitor, AS1842856
A cell-permeable oxodihydroquinoline
MilliporeSigma™ Calbiochem™ Estrogen Receptor Antagonist, ICI 182,780
A cell-permeable estrogen antagonist. More effective than tamoxifen in reducing estrogen receptors in breast tumor cells.
MilliporeSigma™ Calbiochem™ Adenosine A1 Receptor Antagonist I, DPCPX
A blood-brain barrier permeable xanthine derivative that acts as a highly selective antagonist of Adenosine A1 receptor (A1R; Ki
MilliporeSigma™ Calbiochem™ SKF-97541
A highly potent agonist of GABAB receptor. Shown to be about 10-times more potent than baclofen.
MilliporeSigma™ Calbiochem™ Withaferin A, Withania somnifera
A cell-permeable steroidal lactone that displays antitumor, anti-inflammatory, radiosensitizing, and immunosuppressive properties.
MilliporeSigma™ Calbiochem™ TCPOBOP
The most potent known member of the phenobarbital-like class of cytochrome P450 (CYP)-inducing agents.
MilliporeSigma™ Calbiochem™ IRE1 Inhibitor III, 4μ8C
IRE1 Inhibitor III, , CAS 14003-96-4, is a cell-permeable. Covalent inhibitor of IRE1 RNase activity (IC50 = 550 and 45 nM, respectively, with 0 & 16 min preincubation in RNA cleavage assays).
MilliporeSigma™ Calbiochem™ (+/-)-Atenolol
Selective β1 adrenergic blocking ag